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Diabetes 101 - Prescribed Medications For Type 2 Diabetes

By Willie Anderson


The primary treatments for type 2 diabetes are usually diet modification, control of blood sugar levels, regular exercise and weight control. Sometimes, these treatments can't be enough to lower blood sugar levels down to the normal ranges. The second line of treatment is to take medications for type 2 diabetes. There are 2 kinds of these medications: the oral pills and the insulin injections.

How do medications for type 2 diabetes work?

In men and women with type 2 diabetes, their blood sugar amounts are as well substantial. These superior amounts of blood sugar occur for the reason that as opposed to getting into the cells where it genuinely belongs, the glucose remains inside the blood. For that glucose to pass inside the cell there have to be insulin, and this cell ought to really be "hungry' for glucose.

In type 1 diabetes, men and women impacted cannot make insulin. For them to maintain their blood glucose levels down within the typical ranges, they need insulin shots. Meanwhile, for men and women affected with type 2 diabetes, they have two complications:

1. They can't make enough insulin for the glucose absorption in the cells, and

2. The cell bodies don't take the glucose as willingly as they should be.

There are 5 classes of medications for type 2 diabetes, and they work in different ways to maintain normal blood sugar levels:

1. Sulfonylureas

Sulfonylureas can stimulate the cells of the pancreas to secrete more insulin for sugar metabolism. These diabetic oils have been used since the 1950s. The first generation drug is chlorpropamide, and is the only sulfonorea used until today. Second generation drugs are glipizide, glimepiride, and glyburide which are taken in smaller doses than the first generation drugs. Sulfonylureas are taken with meals one to two times a day.

2. Meglitinides

Meglitinides can also stimulate the cells of the pancreas to release more insulin. Examples are repaglinide and nateglinide. They are taken 3 times a day before meals.

3. Biguanides

One of probably the most popular drugs underneath biguanides is metformin (brandname is Glucophage). Biguanides can decrease superior blood sugar levels by dereasing the amounts if glucose which is generated through the liver. It also assists the cells to be sensitive to insulin to ensure that glucose is going to be absorbed. Biguanides are taken twice per day and is also taken with meals. Diarrhea can happen to men and women taking biguanides.

4. Thiazolidinediones

Rosiglitazone, troglitazone and pioglitazone belong to the thiazolidinediones group. Thiazolidinediones work in the fat and muscles and can reduce production of glucose from the liver. This drugs are taken twice daily with foods to avoid gastrointestinal upsets. Blood tests must be performed regularly to monitor liver when a person is taking this group of drugs.

5. Alpha Glucosidase Inhibitors

Examples of alpha glucosidase inhibitors are acarbose and meglitol. Alpha glucosidase inhibotrs works by blocking the breakdown of the starches (like potatoes, bread, pasta) inside the intestine thus lowering sugar levels in the blood. These drugs can also slow the breakdown of other forms of sugars like table sugar. Alpha glucosidase inhibitors must be taken with a meal's first bite for them to action during the rise of sugar levels exactly after the meal. Side effects of these drugs include diarrhea and gas.




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